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It contains structural alignments generated using DALI [14], a well established structure comparison method and subsequently superimposed using rigid body alignment method.
Cluster with higher information content may be more interesting to explore since it contains structural fragments with higher sequence conservation possibly due to certain functional specificity, and could be thus prioritized for manual inspection.
It contains structural proteins including many collagens as well as cadherins, laminins, fibrillin and integrins.
On the other hand, it contains structural features of both zanamivir and oseltamivir, the hydrophilic pharmacorphore of 4-guanidino group of zanamivir and the hydrophobic 3-pentanyloxy moiety of oseltamivir.
While deletion of the carboxyl terminal (C -tail domain of the hIP did not inhibit agonist-induC -tailernalization, co-localization or co-immunoprecipitation with Rab5a per se, receptor trafficking was alteredomainesting that it cofthens structural determinant(s) for hIP sorting post Rab5-medidted enotcytosinhibit
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Neither does it contain structural information as in QSAR models [15].
The concentration of CICPs correlates with the evolutionary distances between the sequences used – the closer the evolutionary distances within a region the higher the concentration of CICPs for that region given that it also contains structural or functionally important residues.
PETcofold considers sequence conservation, but its full power is only revealed when the input data contains structural covariance.
Ice contains structural defects wherever water molecules do not align perfectly within the crystal.
They observed that this last measure phase contains structural information that contributed to improving the classification.
This file contains structural, yield, and elemental analyses data of the title compounds 3a 3l.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com