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It contains some adjustable features to make it competent for wide range of patients in terms of height (153 183 cm) and weight.
It is possible that additional modifications might "license" CENP-A containing chromatin, making it competent for kinetochore assembly.
Comparatively, little is known about the series of structural changes that occur on chromatin during de-condensation and render it competent for the initial recruitment of nuclear membranes and NPC components.
This is supported by reports that Uhrf1 interacts with Dnmt1 through the RFTS domain [98], and this interaction may be instrumental in relieving the autoinhibitory effect on Dnmt1, making it competent for DNA methylation.
The occupancy of CD4 and coreceptor binding sites by their respective ligands elicits downstream conformational changes in the envelope glycoprotein gp41, rendering it competent for fusion between virus and target cell membranes [ 18, 19, 40- 43].
In conclusion, Aim24 appears to have an important role in determining mitochondrial architecture by affecting not only assembly of the MICOS complex, but also by organizing complex reactions such as the remodelling of cardiolipin which makes it competent for the formation of respiratory supercomplexes and the architecture of cristae.
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It is not yet clear whether this species points to an alternative route to RP formation, as it has not been reported to form naturally in vivo and it is unknown if it is competent for assembly into full 26S proteasomes.
And Dr. Edwards destroyed another myth -- that sperm needed to be exposed to secretions in the female reproductive tract before it was competent for fertilization -- by showing that freshly obtained sperm worked fine.
"It was competent for disciplinary tribunal to impose the additional sanction of prohibiting registrations of any new players of 18 years or older for a period of 12 months," it stated.
That guarantees it being competent for many different tasks of biomedical research, including gene therapy, metastasis detection, cancer diagnosis and drug discovery and development [ 1, 2, 5, 6].
Finally, we show that proteasome inhibitors can partly rescue the CMG2 protein, which then properly folds, is released from the ER, and targeted to the cell surface where it is competent for signalling.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com