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This can make it challenging to test between different therapies.
However, some of the measures assess overlapping constructs, making it challenging to test the conceptual model.
These multiple subpopulations, whose properties and relative contributions to tissue homeostasis can be difficult to measure over extended periods of time and often generate debate (e.g. [ 16, 17]), make it challenging to test quantitatively whether cell cycle control follows the pedigree-depth minimization principle.
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While it might be challenging to test with wild flies, it should be possible to vary the laboratory diet, especially plus/minus cactus powder to note any effect on TAG amount or composition.
However, it has proved challenging to test these theories in experiments because it is difficult to say for certain that a given decision was clearly due to the value or a feature.
However, it has been challenging to test this hypothesis in human cerebral cortex.
It would be challenging to test this idea through studies of tube formation because the impact of CRACR2A-L on this process was relatively small.
Numerous inhibitors of various pathways that have been implicated in endocrine resistance are in development, and it would be challenging to test all of the various combinations with different endocrine therapies in clinical trials.
Because Aβ toxicity is observed when this peptide is secreted in the fly model of AD (Finelli et al., 2004; Iijima et al., 2004), it was therefore challenging to test the toxicity to yeast of Aβ species entering the secretion pathway.
Youngsters are challenged to test their physical and mental abilities.
Overall, observations indicate that physicians found it challenging to communicate test results to patients.
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