It is noted that mathematical models cannot be validated with respect to the allowable value of predictors.
Given that true cluster distributions cannot be known in the absence of complete sampling, the model cannot be validated by using it to derive known cluster distributions.
However, this approach has its limitations because separate genes cannot be validated with a gold standard, nor can they be excluded, as there are genes in this set that are similarly differentially expressed between MSCs in vivo vs both osteoblastomas and osteosarcomas.
The challenge is that there is an important sense in which diagnoses cannot be validated at all, if by "validation" we mean "shown to be a real disorder".
Since the performances of the PIDs and the SL-FLCs are highly dependent on their tuned gains it is concluded that the reported performances of these controllers cannot be validated.
"It's antithetical to the basic norms of science to make claims that cannot be validated because the necessary data are proprietary," he wrote.
It plays an important role in helping make informed decisions even when there is inadequate or incomplete information because it provides a framework to process available information with minimal reliance on assumptions that cannot be validated.
Because the validation step highlight the fact that the sensor cannot be validated for all the operating points, the model is modified in order to obtain a fully validated sensor in the whole speed range.
Due to this discrepancy, previous studies concluded that the stochastic QSSA cannot be validated using the deterministic QSSA, leaving open the question of alternative validation methods.
