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Second, each participating mRNA is allowed to be targeted by only some of the participating miRNAs, but it cannot be targeted by other miRNAs.
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However, a significant disadvantage of the method is that specific genes cannot be targeted using this method, as it generates a library of randomly integrated YFP cassettes that subsequently requires extensive screening.
It is also possible that HOXA10 3'UTR is mutated and cannot be targeted by miR-135a in MCF-7 cells.
The lack of attention afforded to barrier identification is surprising given its importance when developing interventions: if important barriers are not identified, they cannot be targeted, limiting intervention effectiveness.
But some strains cannot be targeted.
They cannot be targeted in the way that a few hundred factories can.
Basking sharks became a protected species in 1998 meaning they cannot be targeted, retained or disturbed in British waters.
Some scientists dismiss fears of bioterrorism via influenza, because flu viruses would not make practical weapons: they cannot be targeted, and they would also infect whoever deployed them.
What that really means hinges on how Russia and the United States define legitimate opposition groups that cannot be targeted under the deal, and how they define areas where Nusra is present.
If so, Mr Xi has overturned what has long appeared to be a party rule that serving and former members of the Politburo's standing committee cannot be targeted for corruption.
However, radiation dose delivery by external beam cannot be targeted at the cellular level.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com