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Since the spatially distributed disturbance is infinite dimensional, it cannot be compensated by the typical disturbance observer, which is designed by finite dimensional approach.
This means that if the phase difference of T is too large, it cannot be compensated completely.
Collectively, these data show that the impaired thymic generation of Treg cells in IκBα-SR Tg mice is rather due to a Treg cell-intrinsic defect than an extrinsic one, because it cannot be compensated despite the presence of wild-type derived T lymphocytes and soluble factors.
This led to the abrogation of TRK-T3 induced differentiation and transformation, thus demonstrating that signalling through tyrosine 291 is essential for oncogene activity and it cannot be compensated by possible TRK oncogene-specific signal transduction pathways.
Deputy Minister of Labour and Social Welfare Goran Kusevija said that "the loss of the parental home is the largest loss - it cannot be compensated and it may have adverse effects on child development.
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I might be required by my non-egoist morality to make a sacrifice for which I cannot be compensated (or pass up a gain so large that passing it up will not be compensated for).
It appears that Hsp90α must be present at least during the first wave of spermatogenesis, and its absence cannot be compensated by Hsp90β and has long lasting consequences even if Hsp90α expression resumes later.
Previous studies [ 41, 42] demonstrated that IL-23/IL-17 IL-23/IL-17 IL-23/IL-17r the developathwayf severe schistosomessentialuced immunopathology and its absence cannot be compensated with other mechanisms.
In some inflammatory models, the requirement of one CXCR3 ligand dominates, and its deficiency cannot be compensated for by the presence of the other ligands.
Decreased GR activity may lead to the depletion of glutathione if its loss cannot be compensated for by the synthesis of new glutathione molecules [ 65].
From these results, we conclude that Tfcp2l1 is the major mediator of ES cell self-renewal downstream of LIF/Stat3, and that it exerts functions that cannot be compensated by other LIF targets.
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