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Another result, coming from embryonic gene expression studies with recently developed chip technologies, was that one and the same gene product can be expressed at different stages of development and in different tissues, and that it can be implicated in quite different metabolic and cellular functions.
The increased transcript level of p62 found here may suggest that it can be implicated in physiopathology of protein aggregation and/or it is a natural response to the pro-inflammatory conditions occurred in these infected subjects.
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The aim of this study was to explore whether Ecrg4 and its product augurin, can be implicated in CNS development and the response to CNS injury.
It appears that both cn-LOHs and CNVs can be implicated in somatic mosaicism which shows a great complexity and plasticity of the human genome.
Since the Killer cell lectin-like receptors (Klra), which are also subject to monoallelic expression, have previously also been reported to be deregulated in transformed MEFs and tumors that are mutant for Smchd1 [ 34], it will be interesting to determine whether Smchd1 can be implicated in other forms of monoallelic expression (that is, the olfactory receptors, T cell receptors).
Although the precise role of these genes in NETs is unclear, given the known roles in neuroendocrine development, it seems plausible that activation of neuroedevelopmental pathway (s) can be implicated in NET proliferation.
Leukotrienes can be implicated in the inflammatory mechanism at play in it.
Similarly, many other factors can be implicated in late life dementia, reflecting the variable pathways by which it can arise [ 10].
Moreover, the implications of this study are beyond HD patients and can be implicated in all clinical states associated with primed PMNLs and accelerated atherosclerosis such as hypertension and diabetes.
At the same time, Lockwood said, "we know intervention works best when it occurs early in a disorder or disease" -- a relevant point in cases where a treatable mental illness can be implicated in a cruelty crime.
In recent years, researchers have been sorting through the multiple bacterial species that populate the microbiome, asking which of them can be implicated in specific disorders.
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