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Sometimes malsynthesis of an unknown enzyme(s) or receptors are responsible for a chronic disease and it becomes difficult to identify them by merely observing symptoms.
Furthermore, when undesirable outcomes are considered such as hazard to human(s), it becomes difficult to identify strict statistical targets for what is acceptable.
Unfortunately, with the lack of preexisting relationships with the patient, limited knowledge of opioid abuse and the limited time that the provider has with the patient in the emergency setting, it becomes difficult to identify individuals at risk for opioid abuse.
Therefore, if there are no or very little morphologic changes, it becomes difficult to identify drug targets.
Some clinicians initiate therapy of MT as a once daily dose; however, with the MEPS database, it becomes difficult to identify these patients.
When metastases are closely spaced, or as the area of skeletal involvement overlaps over time, it becomes difficult to identify individual sites.
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The organisms showing Trend III or Trend V often exhibit zig-zag patterns in their GC-skew and other skew curves and it sometimes becomes difficult to identify the ter regions of their chromosomes unambiguously.
Eventually, it may become difficult to identify the endosymbiont as the descendent of a free-living organism.
It had already become difficult to identify qualified applicants to many medical professorships.
However, under disturbed conditions, as shown in Fig. 2b, UHR emissions become difficult to identify, especially outside of the plasmasphere.
Furthermore, for a large dataset (for example over a hundred compounds), such as those produced using high-throughput techniques [26], the heatmap quickly becomes cluttered and individual compounds become difficult to identify.
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CEO of Professional Science Editing for Scientists @ prosciediting.com