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Hailed as progressive when it opened in 1940, it became functionally obsolete as vehicle and river traffic increased.
In contrast, although expression of CR3 was not increased, it became functionally activated during fusion and was located on the extensive membrane ruffles created by excess plasma membrane arising from macrophage fusion.
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It is possible that the XIP members became "functionally redundant" during evolution and the above TIP and NIP members could have substituted the functions of the redundant XIPs.
However, this distinction is not easy to make, as it requires determining the point in evolutionary time when a process related to human disease became functionally conserved.
One group, the Lucy species, relinquished the arboreal habitat and became functionally committed, long-distance walkers.
Retail business shriveled, the tonnage of goods being delivered at New Jersey ports slipped and the "monster" industrial buildings — as Cushman's industrial specialist, Stanley B. Danzig, terms anything over 750,000 square feet — became functionally obsolete, in some cases before they were finished.
At 3 month 5 patients (6%) remained fully/severely functionally dependent, 3 (4%) were partially functionally dependent, 16 (20%) became functionally independent with help and 56 (70%) became functionally independent.
Further enzymatic study and functional analysis will provide insights into how this multiplicity of laccases evolved and became functionally differentiated for lignin degradation, fruiting body development and fruiting body coloration.
Subsequently we tested whether cytokine rescued T cells became functionally equivalent to non-tolerant T cells, or whether they remained cytokine dependent upon secondary peptide stimulation.
While BORIS is widely expressed in reptiles and monotremes, expression was shown to be gonad-specific in marsupials and eutherians, indicating that BORIS became functionally specialized during mammalian evolution in concert with the evolution of genomic imprinting [18].
During these processes, the cellulase gene became functionally integrated into the nematode's biology.
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CEO of Professional Science Editing for Scientists @ prosciediting.com