Sentence examples for it activates through from inspiring English sources

Instead, it activates through heterodimerization with other members of the family (EGFR and Her3, in particular) when they are bound to ligands (Citri and Yarden, 2006; Baselga and Swain, 2009).

Nonetheless, it activates Akt through phosphorylation at Ser473 (ref. 65 ) and thus negatively regulates autophagy.

It activates ENaC through several pathways [ 33] and among these pathways, inhibition of E3 ubiquitin ligase, neural precursor cell-expressed, developmentally downregulated protein 4-2 (Nedd4-2) seems to be the most important.

Active PKD has a dual effect on CERT transport activity: on the one hand, it directly phosphorylates and thereby deactivates CERT (Fugmann et al., 2007), on the other hand, it activates CERT indirectly through activating PI4KIIIβ, which triggers synthesis of phosphatidyl-inositol-4-phosphate (PI4P).

Once it is activated through progesterone induction, it activates a series of gene cascades leading to completion of the meiosis process.

It activates viral gene expression through TAR interaction.

It activates the signal transduction cascade through tyrosine phosphorylating its protooncogenic c-Met receptor.

Thrombin also activates cellular protease activated receptors (PARs) through which it activates components of the inflammatory pathway.

The inhibitory effect of TGF β on autophagy should not be a surprise as it is known that it activates the autophagy inhibitor mTOR through the PI3K AKT pathway.

The receptor encoded by Ryk functions as a co-receptor with Frizzled for Wnt ligands and binds to Dishevelled, through which it activates the canonical Wnt Pathway (Lu et al. 2004).

MMP-2 is secreted from the cell as an inactive zymogen and, once outside, it is activated through cleavage of its pro-domain [14].