Sentence examples for it's highly difficult from inspiring English sources

"My perception right now is the effects of calorie restriction are multiple," he said, "so I think it's highly difficult to find one, or two or three drugs that will mimic such a complex effect".

Hence, it is highly difficult to ensure the long-term guaranteed path from one node to the other node.

Since it was highly difficult to acquire the population for each cell, it was assumed that population locations complied with residential blocks.

He noted that it was highly difficult to harmonize the two.

It is highly difficult to apply such a criterion in septic shock.

Not rarely in clinical routine it is highly difficult to evaluate the volume status of a patient.

Since there is limited availability of early-stage human embryos used for hESC derivation, it is highly difficult to obtain HLA-matched hESCs for all patients.

However, a significant obstacle to effective model-based studies comes from the fact that it is highly difficult to achieve the values of model parameters.

This study provides no information on informal caregivers who did not respond, as it was highly difficult to assess demographic data when refusal was stated during the invitation phone call.

He suggested it would be "highly difficult, as difficult or more difficult than the original production".

"We do make every effort to track down perpetrators, but it's extremely difficult as these are highly-organised operations".