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That basic notion — that the world is there for us, and if it doesn't serve our purposes it's dispensable — has produced the devastation of vast areas.
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Finally, RAP1 binds telomeric repeats through its interaction with TRF2 although it is dispensable for telomere capping (Martinez et al., 2010; Sfeir et al., 2010).
Its degradation, though, would indicate that it is dispensable for the HEZs seen in such cells.
By contrast, it was dispensable for heat induction through the canonical HSE.
Music is often treated as cultural décor, but if it were dispensable then we ought to be able to imagine life without it, and we cannot.
Administration of cyclophosphamide (CTX) was required to suppress formation of anti-canine FIX antibodies for AAV2-treated animals, whereas it was dispensable for those treated with AAV1-F9.
Therefore, it is dispensable to seek for the optimal power allocation to maximize the object (29).
Together, our data demonstrate that TSC1 plays important roles for B cell development, but it is dispensable for GC formation and serum antibody responses.
Lack of sequence conservation in this site together with the low inhibition by i6 suggests it is dispensable for the CNOT7 interaction, but could be useful for design of inhibitors targeting specific Tob/BTG family members.
Consistent with this, while Drosophila Crk binds Mbc, it is dispensable for myoblast fusion [11].
On the other hand, it is dispensable in Salmonella enterica [64].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com