Exact(1)
The proximity of nucleosomes and the methylation, phosphorylation or acethylation states of their constituent histones also affect the chemical environment "seen" by the TF (reviewed in:[8] ) The same holds for other proteins that may be bound near the BS, whose presence can either inhibit binding of the TF on which we focus, or enhance binding by modifying it's conformation, or that of the DNA.
Similar(59)
The adjacent Ala59 ends a three-residue alternate conformation and is deposited with separate backbones, and although Ile47 is not, it should be: conformation A is non-ideal with a 0.38 Å Cβ deviation (Lovell et al., 2003) and 0.59 Å between alternate Cβ's.
Controlled electropolymerisation of dopamine around the complex served to both entrap the complex, holding the aptamer in, or near to, it's binding conformation, and to localise the PSA binding sites at the sensor surface.
In all figures, the rigor conformation was chosen because it is the conformation of Myo1A under the conditions most commonly employed to study the structure of Myo1A about the actin core bundle.
Gp41 antigenic function is conformation dependent, therefore we planned to insert a linker sequence onto the MPER core region in order to have the MPER epitope presented on the Ad capsid as close to it's natural conformation as possible [33].
The modeling suggests that it is the conformation of the protofibril per se, both its twisted surface and its spiral curvature, that promotes the assembly.
It is the conformation of these Dreierdoppelketten that alters the subcell from orthorhombic to monoclinic: the double chains in 11 Å orthotobermorite display 2 mm symmetry compared with 2/ m in 11 Å clinotobermorite (Bonaccorsi & Merlino, 2005 ▸).
One is similar to the conformation found in the apo mAChE crystal structure and it is termed apo conformation.
By blocking protein degradation by the proteasome or protein synthesis globally, both of which lead to a decrease in the abundance of the 'open' conformation and a corresponding increase in the 'closed' conformation, it was established that the two conformations of the Keap1 Nrf2 complex represent two phases of a cycle.
While no Mg2+ was detected in the MglA ·GDP conformation, it is present in the GppNHp conformation and forms a canonical bi-dentate complex with the β- and γ-phosphate oxygens.
Infrared spectroscopy is used extensively to study sugars and other carbohydrates because it is sensitive to configuration, conformation, and hydrogen bonding [ 18, 19].
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