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In all GGT proteins characterized so far, a conserved threonine (Thr) acts as nucleophile during it's auto-processing into small and large subunits as well as during it's catalysis reaction [ 1– 3].
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The first committed step in Lipid A biosynthesis is catalysis by LpxC, a zinc dependent deacetylase.
The key problem for the direct conversion of solar energy in photoelectrochemical cells is catalysis.
Their best characterized function is catalysis of maturation of spliceosomal and ribosomal RNA by guiding methylation and pseudouridylation of target RNAs in sequence-specific manner [39].
Therefore, it is called "pseudoliquid" catalysis.
It is favorable for catalysis only when γ is very low.
It is shown how catalysis science changes from a descriptive science, focusing on structure-performance relations to a predictive science, with a basis in molecular mechanistic understanding.
It is attractive for catalysis with well documented high activity for hydrocarbon conversions but as a transient product MCM-56 presents novel challenges with regard to synthesis and activation.
The phosphodiester bond addition cycle is characterized by the 2-Mg2+ catalytic mechanism, and it is thought that catalysis is supported by a closed conformation of the RNAP trigger loop.
By contrast, D1064 is mutated in several organisms to residues incapable of proton transfer (Additional file 1, Table S2), indicating that it is dispensable for catalysis.
The proposed catalytic base residue in the OspF family (Lys136) is well-conserved in LanL enzymes, and mutation of the corresponding Lys80 in VenL-ΔC shows it is essential for catalysis of the β-elimination reaction.
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