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We refer to the ensemble of sequences that bind a TF as it's Binding Motif (BM).
However the saturated double bonds in the isoquinoline ring might alter its aromaticity [ 42], thereby interrupting it's binding with the G-quadruplex (Fig. 5a).
One of these concerns the extent to which a TF's functionality depends on the location of it's binding site (BS), and another-the relative regulatory importance of different regions of the promoters of higher organisms.
Webb's legislation is simple, direct and more importantly it's binding.
It's binding to a site extraneous to the P-loop explains CTP's incapacity to donate a phosphoryl group despite its strong binding to the enzyme.
If the deal goes through, because this is what's known as a "scheme of arrangement" rather than a standard takeover offer, it's binding on all shareholders, even if they didn't vote for it.
Similar(39)
The glycosylation of rhinocerase might, however, limit its functions when it is binding to large biological substrates and inhibitors.
In the majority's view, the union agreed to the arbitration clause, and it was binding on all of its members.
None of it is binding unless you also sign a contract to bind yourself under British law.
A vote against the remuneration policy is significant as it is binding vote while the vote on the remuneration report – covering last year's pay – sends a clear message about investors' views on pay deals but is advisory.
Before departing, Judge Sidney Brooks of the United States Bankruptcy Court declared Pacific's bid the winner, saying, "As far as this court is concerned it is binding".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com