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Several methodological issues of studies need to be addressed.
103 Meta-analysis has been used to deal with the issues of studies with small numbers.
A second limitation is that effect of educational interventions cannot be estimated - rather issues of studies on educational research will be compiled.
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They also pay special attention to issues of study design and quality of the trials reviewed.
We discuss issues of study design as they relate to studies of the placenta and human brain disorders.
As study design and sensitivity are particularly demanding in studies using pre-emptive dosing of analgesics, the placebo groups were analysed for issues of study sensitivity.
Contemporary issues of study include developing tools for knowledge transferring, understanding the unique characteristics of knowledge transfer in global projects, and discussing the social aspect of brokering knowledge.
Accompanying these studies, consensus on key issues of study design and analysis protocol emerged [3], [4] However, despite these efforts, most of these signatures have not yet been introduced into clinical practice.
Although several promising methods are available, the relevant issues of study design and data analysis for detecting interactions including sample size for a desirable power and the efficiency of statistical methods have not been well explored.
Other concerns focus on issues of study design.
Outcomes other than those studied here may be more sensitive to the issues of study quality.
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