Central to any discussion of techniques of liver resection are the linked issues of indications and resectability.
However, as in the setting of acute trauma, significant issues of cost, indications, laboratory monitoring, safety, optimal dose, and use with blood products and other hemostatic agents remain to be established for rFVIIa use in patients without acute trauma who do not have hemophilia.
A major strength of this study was the inclusion of detailed psychopathological data which eliminated issues of confounding by indication.
This leads to the challenge of studying medication effects on endpoints in the observational setting, where issues of confounding by indication are challenging to deal with.
A randomized trial will be the only way to sort out the issues of confounding by indication, balance the risk of mortality from bleeding versus a potential benefit on breast cancer survival, and determine a causal relationship between breast cancer prognosis and ASA.
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They require information about the issues of concern and an indication of the hazards and the risks that need to be addressed (Briggs 2003).
Despite the recent global awareness of bacterial resistance issues and indications of the growing antibiotic resistance in DCs, epidemiological evidence remains limited and available data are not sufficient to draw a true, recent, and accurate picture of antibiotic resistance in DCs among neonates and particularly in the community.
Not getting the highest grades you are capable of is a behavioural issues, not an indication of Special Educational needs.
Such research must effectively address the important issue of confounding by indication in order to produce clinically meaningful results.
