The court's decision last May to hear the Philip Morris appeal, Philip Morris USA v. Williams, No. 05-1256, suggested an effort to find a new center of gravity on an issue of considerable interest to the business community.
The prospect of Scotland breaking out of the union with England, Wales, and Northern Ireland may not exactly be a threat to global stability, but it is nonetheless an international issue of considerable interest, certainly to European political players and further afield, too.
Aerodynamic optimization has widely become a issue of considerable interest to determine the geometry of an aerodynamic configuration amidst certain design constraints.
Therefore, investigation of new agents for treatment of worm's infestation with the ability of high toxicity to parasites and less resistance and residual is the issue of considerable interest for pharmacists and veterinarians.
Choosing the appropriate method to assess the cost of organ recovery is an issue of considerable interest to health economists, hospitals, financial managers and policy makers in most developed countries.
Choosing the appropriate costing method to estimate accurate costs in healthcare is an issue of considerable interest to health economists for economic evaluations, to hospitals for financial management purposes, and to policy makers in most European countries.
These conformations will in turn impact on the conformational space that will be covered by the substituents, making the determination of the cycle's conformation an issue of considerable interest.
The adventitious presence of transgene containing seed in conventional crops is an issue of considerable interest; a model to predict levels will aid regulators and help to address concerns of farmers and consumers.
Understanding what factors underlie the disruption of the circadian system, including melatonin production, remains an issue of considerable interest [24], [34].
The mechanisms underlying TGFβ/ALK5-dependent Ras/Erk1/2 activation is an unresolved issue of considerable interest due to its established role in providing a growth advantage [ 58].
