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However, due to publication bias and due to quality issues in the trials studying GS, it may well be that reported effect sizes are exaggerated.
The primary tolerability issues in the trials were gastrointestinal adverse events, particularly during the first weeks of use, although the rate of nausea during startup with exenatide QW was lower than that with the related agents, exenatide twice daily and liraglutide once daily.
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Last month, Judge Kaplan called the issues in the trial "narrow and well-defined".
Trying to short-circuit that, the appellate court invited a technology expert to hold a computer-technology seminar for the judges next month, one that would not touch upon the issues in the trial.
One of the key issues in the trial was less theological or scientific, but philosophical.
In the recently published biography "Brown Eyed Handsome Man: The Life and Hard Times of Chuck Berry," (Routledge), Bruce Pegg writes: "The issue in the trials was one of Janice Escalanti's age.
Dahlia Lithwick makes the good point that the Administration, by going out of its way to keep cases seeking accountability for torture out of court, is making sure that torture will only become an issue in the trials of people in court for other reasons — like, say, knocking down the World Trade Center.
A methodological issue in the trials reviewed has been the difficulty in diagnosing 'pure' VaD as the criteria used are relatively insensitive (that is, will miss a proportion of those with significant cerebrovascular disease) and many of those fulfilling probable VaD criteria have mixed pathologies (typically AD and cerebrovascular disease) [ 42].
31, 1999, article at issue in the trial.
"The issue in the trial was the distinction between murder and manslaughter.
The state of mind of Mr. Duncan is a crucial issue in the trial of Andersen.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com