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But Clinton's allies argue her advocacy on women's issues has made a profound difference.
A recent series of personal issues has made navigating her already complex life more difficult, close associates said.
In many respects, the growing liberalization of America on social issues has made the culture war an attractive battleground for Democrats – perhaps dangerously attractive.
"The recent attention to radiation dose issues has made the user base more receptive to these types of verification procedures," Mr. Fisher said.
Mr. Gupta's leadership on global health issues has "made a real difference in the lives of literally millions of people around the world," Mr. Gates wrote.
The experience of being an expert witness on these issues has made me feel a great deal safer on the streets of London.
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Very few political issues have made me vacillate as much as the Scotland independence referendum.
Ms. Crowley said that real estate issues had made her rethink her art.
The impossibility of insuring her and other issues have made it impossible for us to go forward".
Stacey Hanuska, 34, of Pottstown, Pa., said reading about the Lululemon issues had made her even more of a fan of Athleta.
But voting patterns provide a glimpse of how changing demographics and issues have made the city's suburbs increasingly fertile for Democrats.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com