Current protocols for human pluripotent stem cell (hPSC) expansion require feeder cells or matrices from animal sources that have been the major obstacle to obtain clinical grade hPSCs due to safety issues, difficulty in quality control, and high expense.
Dentists described strategies to resolve three critical issues: missed appointments (organisational issue); difficulty in performing non-covered treatments (biomedical issue); and low government fees (financial issue).
This review first examines the issues, difficulties and challenges in prediction of material behaviors by summarizing and critiquing the existing major analytical approaches dealing with material property modeling.
This is primarily due to legislative issues, economic issues, difficulties of implementing this technology in some ornamental plants, as well as how these techniques are publically perceived, particularly in Europe.
For example, it encountered winner-takes-all competition, disintermediation (when service providers and clients took transactions off the platform to avoid the platform's 20% commission fees), the rise of fake transactions, member management issues, and difficulties in delivering satisfactory services to large enterprises.
The large efforts focused on manufacturing had blinded the enactors for the issues and difficulties in optimizing performances of solution processable polymers.
The importance of canonic works is not that they are peerless exemplars of an idiom or style but rather that they raise issues and difficulties in an exemplary way.
For one, cryptocurrencies as an asset class are riskier than what the average investor is comfortable with; and secondly, learning to buy and trade cryptocurrencies can be an ordeal in itself, with security issues and difficulties in working with multiple exchanges.
She talked to me about friendship issues and difficulties in school.
There are many issues and difficulties in the curation process.
