With this gallery Mr. Gober lays out some of the issues, affinities and troubled histories that fuel his art.
The department did not request bids from a number of out-of-state banks that, like MBNA, issue affinity cards.
We give an overview of FISH probe design, covering issues of affinity and specificity of probes, probe backbone options, cellular targets, and accessibility of target sequences.
The applications for molecules that bind proteins keep expanding, and issues of affinity, specificity, robustness, and time for development are in focus.
In attempting to design improved inhibitors of MBLs which might be of clinical value, there are two distinct issues: improving affinity and retaining a broad spectrum of activity against MBLs of all classes.
When the chelation by indicator dye becomes an issue, its affinity (the inverse of dissociation constant Kd) and concentration are two important factors to be considered.
These are not always captured by homology models, especially the issue of affinity.
As described in another paper (Aloj et al., this issue), the affinity of all these 12 peptides was in the same low nanomolar range.
Several proteins issued from affinity chromatography and immunoreactive after Western blot with R 435 or R 706 were submitted to N-terminal amino acid sequencing.
TCR tetramers [ 70] and pMHC display methodologies [ 71- 74] have not gained widespread use for antigen discovery, and they tend to be hampered by a combination of low solubility and binding affinity issues, as well as the difficult logistics of large-scale screens.
