And certificate letter was issued for the study with their signature.
It is a very important issue for this study, as such satellite configuration can provide more data for adjacent LT sectors, but can lead to considerable differences in simultaneous comparison of satellites measurements.
An issue for this study concerns generalizability.
The central issue for this study was, Which endometriosis therapy is currently the most successful technique?
This issue for this study has been in part addressed by others (Borak et al., 2011 ) and will be discussed further in the case-control review.
The most relevant issue for this study is that the null distribution of p-values (for transcripts known to be equally expressed) is not uniform.
The frequently reported gate-keeping role of service providers [ 25- 28] or lack of support from clinical colleagues [ 8] was therefore not an issue for this study.
Although missing data is not expected to be a major issue for this study, the nature and pattern of the missingness will be carefully considered — including in particular whether data can be treated as missing completely at random (MCAR).
Snowball sampling of HCPs in stage 2 may have introduced bias; however, Northern Ireland has a small healthcare system and we recruited all of the key respiratory physicians, nurses and physiotherapists at each hospital site so this is unlikely to be a significant issue for this study.
