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However, two limiting issues have to be pointed out in this context: First, an early improvement of HPA axis hyperactivity (e.g. within 1 week of treatment) is not necessarily followed by a favourable response and therefore is not a sufficient condition for a beneficial treatment outcome.
Another important issue that needs to be pointed out is the specification of optimal number of features [23].
One issue that needs to be pointed out with the MateBook X is that not all versions of the machine come with a trusted platform module (TPM) – the small chip built into the machine that securely stores encryption keys.
To clarify this issue, it must be pointed that among the remaining ones, nine had an aggressive disease defined by ⩾50% replacement of liver parenchyma.
Several important methodological issues should be pointed out.
Uefa is investigating the issue after it was pointed out to them by Tottenham's officials.
This issue was pointed out to be critical, at least in proton-therapy by Britten et al., 2013 [ 47].
"The day the new policy was announced," Mr. Spies said, "two issues were pointed out to the manager".
Van Der Kleij doesn't deny these are issues to be addressed, but he points out that a lot of the work has already begun.
This issue is pointed out in the revised manuscript more clearly.
The second issue Broussard is pointing to has to do with managerial incoherence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com