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He then diverted the question away from Mr. Adelson's gambling interests and toward his support for Israel, an issue of utmost concern to the religious audience.
Over the past five decades, the drug resistance of Plasmodium falciparum has become an issue of utmost concern.
Thus, it is an issue of utmost concern to give proper treatment to industrial effluent so that it becomes pollution free by the time it is disposed off into the aqueous systems.
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Flutter and buffeting are both issues of utmost concern in the wind-resistant design of long-span bridges.
North Korea's state-run news agency KCNA, meanwhile, said Monday that Kim had "expressed his will and conviction that a great progress would surely be made in solving the issues of utmost concern of the world and in attaining the goal set forth at the last talks with the projected second DPRK-U.S. summit talks as an occasion".
Perhaps this issue is of utmost concern for self-reported outcome measures using questionnaires about tinnitus handicap or distress, because clinical intuition suggests that the psychological response often naturally diminishes over time.
Despite the encouraging preliminary report on VASST showing an improved 28 and 90 days' survival in patients with less severe septic shock (Congress of the European Society of Intensive Care Medicine, Barcelona, 2006), any safety issue that could limit the clinical use of AVP is a matter of utmost concern.
Moscow's security has been a matter of utmost concern amid a rash of attacks by Chechen terrorists.
With the advent of big data, privacy has been a topic of utmost concern.
The situation in Sub-Saharan Africa, where there has been a continuous rise in the number of undernourished the situation is, to say the least, of utmost concern.
"Immigration issues will always be important to certain groups but the downturn in our economy is of utmost concern".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com