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Perhaps the most likely explanation for both types of mutations is the issue of depth.
Arksey and O'Malley demonstrate that this definition emphasises the need for breadth in the coverage of the available literature whilst leaving open the issue of depth of coverage according to the purpose of the review.
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The issue is the degree of mental work needed to operate with this new modality, with issues of depth perception and anatomy recognition currently making these procedures extremely difficult and unlikely to be practically applied or taught.
There are more issues of depth.
To address the issue of sequencing depth, we performed additional data analysis using the first 7 million sequencing reads of 010_M and 221_M data (Additional file 1: Table 4&5).
A larger aperture also means more background blur (which is a related, but not identical, issue to depth of field It's as simple as this: a smaller aperture means more depth of field, a larger aperture means less. A larger aperture also means more background blur (which is a related, but not identical, issue to depth of field ).
Part of this is an issue of time-depth.
The depth of impact, the durability of impact and the secondary effects are critical to poverty reduction, and this is nowhere more true than when jobs are created (the issue of breadth vs depth will be covered in more depth in another blog in our series).
It was always heartening to see a cartoonist discussing issues of such depth with his readers, some of whom were so young that they were learning how to read using the strip or had never thought about what happens when we die.
As highlighted by restraints in the present study, issues of sequencing depth, sample size and unbiased data generation are of foremost importance.
The present study adopted qualitative methodology and such an approach is especially useful in elucidating issues of context, depth, detail, and content [ 7].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com