This paper shows that in the CGV region the crucial issue of temperature correction becomes especially simple, which is particularly beneficial when higher-order helical modes are also exploited for tomography.
In our opinion, the issue of DT correction requires further investigation using large number of dataset from patients with different body shapes and sizes to fully understand the interdependence between primary photons count losses and patient's body shape, scatter, and primary photon count rates.
First, we have not addressed issues of optimism correction for small samples, and this remains a topic for future research.
Further work is needed to address the issues of optimism correction and how multiple imputation should be applied for internal and external validation.
Few studies addressed the specific issue of a PS correction of repeated-measures designs.
Lastly, masking of the CBF maps with the segmented T1 image did not sufficiently address the issue of partial volume correction (PVC) in ASL data because of the sensitive to noise and errors in the partial volume estimates, and the further advanced PVC methods should be performed to balance the spatial and smooth effect in the PV estimates [48].
Although we used the iodine-to-creatinine ratio to overcome the issue of dilution, this correction may not be as effective when samples are extremely dilute.
Although these methods could in some sense be considered to be specifically designed for family data, the fact that the GAW18 data are not nuclear family data (but rather derived from 16 or 20 large pedigrees) raises the issue of whether any correction needs to be made to account for the trios (two parents and a child) selected from a large pedigree not being themselves independent.
28 In relation to its prefrontal projections, the cerebellar cortex simulates the way in which the outputs of prefrontal areas are processed, allowing it to issue feed-forward commands of correction signals back to the frontal lobe circuits.
The test gives one P-value for the whole group instead of one P-value for each gene to avoid the issue of multiple testing corrections.
