Now we turn to the issue of correcting for population stratification in genetic association studies.
Because orphans generally have low QIPP scores it is also possible to meaningfully rank them as a subset of all CDS, selectively filter for high-scoring 'authentic' orphans, and begin to address the issue of correcting for the high percentage of orphans in current databases that are simply an artefact of sampling bias.
The issue of correcting for prematurity is controversial, but the general consensus seems to be the use of corrected age up to 18-24 months [ 33].
There was little variation in the number of correct issues selected between the subgroups (p=0.20).
Across all the participants, the median number of correct issues chosen was two of the five (mean 2.4, range 1 5).
Using the independent samples Kruskal-Wallis test, the number of correct issues chosen was compared in Exercise 1, and the score value assigned was compared in Exercise 2. All the statistical tests were conducted in IBM SPSS Statistics V.21.
The board also had to deal with the painful issues of correcting racial balance in the classroom and of making sure the high school was not tracking students by academic ability.
Castle sidestepped the issue of the correct grading of the women's work and entitlements and offered instead to bring their pay as unskilled workers into line with the pay of male unskilled workers.
Thus, the issue of the correct measure of time occupied considerable attention in 17th Century astronomy, especially because the ability to measure the rate of rotation of the earth is equivalent to the problem of determining longitude, which, for sea-faring nations, was critical for navigation (and hence military and economic dominance).
Last but not least, the issue of ensuring correct SUV calibration is eliminated since all calibration factors cancel out when performing an image-based determination of both TRF slope and c a 0. This observation seems especially relevant for multi-center studies.
