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Challenging the issue of baseline renal function is thus crucial for validating the potential usefulness of biomarkers in clinical practice.
If an interaction is either posited or observed, then descriptive baseline data for the four cells is more helpful; otherwise, the margins are more relevant to the issue of baseline comparability and correspond to the primary analysis.
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My focus in this entry will be on the issue of the baseline, since this seems most fundamental.
Ongoing profiling may allow us not just to ask how these profiles associate with clinical features, but also to address the major issue of whether baseline profiles predispose individuals to disease, or more commonly provide a level of homeostasis that protects them from perturbations that might otherwise push them into a state of ill health.
As regards surgical patients, information provided by the National Confidential Enquiry into Peri-Operative Deaths helps to address the issue of where a baseline for risk might lie [ 4].
In our article [ 1] we addressed the issue of differences in baseline characteristics, namely whether maxillofacial injuries or spinal cord injuries were present.
The first important issue is what the reporting of baseline RA-ILD constitutes, and whether this may have differed between the treatment arms.
"I think it's a baseline issue of parental rights," he said.
As they report in an upcoming issue of Geophysical Research Letters, since 1950 the baseline stream flow the amount coming from groundwater, not over the surface from rainfall has doubled in areas where the trees have replaced the formerly degraded grasslands.
Policymakers have been ambivalent, at best, in tackling the issue of passing a federal baseline privacy law.
The issue of when to take baseline measures for the PIPP when the intervention begins many minutes before the heel lance procedure needs addressing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com