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This issue may be addressed by training models with a larger size and increased diversity, which many times is not an option in QSAR studies, or to circumscribe the model by defining its applicability domain (AD) in the chemical space [81, 82].
This issue may be addressed through the use of contemporary methodology and validated animal models.
One avenue by which this issue may be addressed is web-based medium which affords the use of interactive training tools.
This issue may be addressed in a further study that includes patients who have no corrective intervention during second-look hysteroscopy.
However, this issue may be addressed through the use of a suitably valid and reliable quality of life instrument [e.g. the Multiple Sclerosis Impact Scale (MSIS29)].
This issue may be addressed in future versions of the EQI by attempting to identify better markers of the rural and suburban sociodemographic environment and incorporate those into the EQI.
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The constitution also provides that some issues may be addressed by either the federal legislature or a state legislature.
These issues may be addressed by combining the idea of fast dissolution at the surface with supercritical water oxidation (SCWO).
Through the invent of embryonic-like stem cells – such as parthenogenetic stem cells, male germline stem cells, and induced pluripotent stem cells – some but certainly not all of these issues may be addressed, albeit at the expense of additional concerns.
By implementing biochemical markers in all stages of drug development, novel drug candidates may be identified at early decision points and potential safety issues may be addressed in a timely way, thereby increasing efficiency, reducing costs and prompting efficient allocation of limited resources.
Moreover, very little discussion has actually been dedicated to comparing the two transitivity networks in terms of their individual strengths and/or weaknesses (cf. He et al. 2017); the current paper is an attempt to contribute to this discussion and to outline a series of dilemmas associated with either one or both and how these issues may be addressed.
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