Sentence examples for issue is the observation of from inspiring English sources

An important issue is the observation of bad fixation strength of the prosthetic components to the bone.

Relevant to this issue is the observation that overexpression of p21WAF1 or p27Kip1 in the promyelocytic leukemia cell line accelerates its lineage-specific differentiation (Wang et al, 1998; Zhou et al, 1999).

Another way of looking at this same set of issues is the observation that many people, modelers and nonmodelers alike, seem to believe that one "right" model exists.

A common issue in experiments with magnetostrictive material is the observation of large amount of scatterers.

This is the observation of a fact.

A third issue is the presence of the researchers on the wards on a regular basis for the observations.

One main issue is the dependence of discrete time parameter estimates on the chosen time interval, which leads to incomparability of results across different observation intervals.

An important emerging scientific issue is the real time filtering through observations of noisy turbulent signals for complex systems as well as the statistical accuracy of spatio-temporal discretizations for such systems.

Among the pressing issues is the lack of continuous ground observation in high-elevation regions.

Most telling are the observations of unnamed nurses.

9 Additionally, evidence for this issue is provided by the observation of an association between high levels of C-reactive protein (CRP), a sensitive marker of subclinical inflammation with insulin resistance or components of MetS.