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At issue is the difficulty of allocating the cost of collective action and trusting other parties to bear their share of the burden.
The issue is the difficulty of identifying whether an intervention is misguided tampering or insightful application of tacit knowledge.
However, focusing on the cognitive dimension of the framework, a persistent issue is the difficulty of participants in online conversations to proceed to common understanding and joint construction of meaning.
One recognised issue is the difficulty of accurately measuring the active forms of vitamin D. Advances made include some new methods addressing the potential interference by excluding epimers and isobars.
Another issue is the difficulty of ensuring that sample donors have acted voluntarily and on an informed basis.
One issue is the difficulty of using small animals such as rodents because of the small size and volume of their discs.
Similar(53)
A related issue was the difficulty of attributing long term impact to a single research project.
Another issue is the difficulty in effective validation of a new method presented by wet experiments expect for the cross-validation.
Another issue is the difficulty in identifying the source of unnatural variation, that is, lack of diagnosis, especially when dealing with small shifts.
An example of a logistic issue is the difficulty in planning a meeting with a participant with sufficient time to administer all the tests and questionnaires.
Exacerbating the early discharge issues was the difficulty of maintaining a strong and effective link between hospital and community services.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com