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Studies specifically addressing this issue in the setting of the full spectrum of the acute coronary syndrome are limited.
These varying recommendations for imaging staging for occult metastases in women with newly diagnosed breast cancer reflect the paucity of evidence on this issue in the setting of early stage disease without symptoms suggestive of metastases.
However, both are essentially testing the same conceptual null hypothesis, the hypothesis that there is no conditional association between X* and Y, given X, and thus no potentially useful incremental information in X* for the purposes of predicting Y. Consider now approaching this issue in the setting of an ROC analysis.
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Moreover, those studies rarely addressed the issues in the setting of developing countries.
The present study examined these issues in the setting of a clinical information and evidence evaluation service made available to health care professionals.
Such practices raise serious security issues, which, in the setting of the healthcare system, could place patients' protected health information at risk.
The issue of VOD in the setting of a second myeloablative transplant procedure within 8 weeks of the first was a particular feasibility concern, but these results are not suggestive of increased risk of this complication.
Professor Bliss also addressed the important issue of 'clinical significance' in the setting of 'statistical significance' and provided valuable insights into statistical considerations that are important to the clinician who must make judgments regarding findings reported in the literature.
So does raising the issue in the incongruous setting of an amusement park, through the sarcastic metaphor of a joy ride, force people to confront their nation's political demons?
These issues are also relevant in the setting of current developments of genomic multi-step or single-step prediction methods (e.g., [ 3- 5]).
However, very few studies have addressed this issue in the therapeutic setting of synthetic DMARDs in early RA, a situation which is likely to be most important in resource-limited settings, including sub-Saharan Africa.
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