But, while "tiered access" never influenced the spread of the telephone network, it is becoming a major issue in the evolution of the Internet.
Hotspotting near DSBs opens the possibility that specific genomic regions could be targeted for mutagenesis, and could also promote concerted evolution (coincident mutations) within genes/gene clusters, an important issue in the evolution of protein functions.
Indeed, recent studies have applied evolutionary game theory to key issues in the evolution of energy metabolism.
Key issues in the evolution of polygenetic landscapes included examining the role of tectonics and isostatic uplift, the nature of exhumation rates, climate control and erosion distribution, glaciers and relief production, focused erosion and spatial coincidence, geomorphometry and erosion modeling, and equilibrium concepts such as topographic steady state.
Comparative mapping contributes largely to solve issues in the evolution of individual species, differences and similarities between various species and to characterize functions of genomes by providing a detailed analysis of conservation among orthologous intervals in different species [ 14].
In regards to the first question, I think there may be some interesting issues in the evolution of protein requirements over the long term evolution of the biosphere, but I don't find that this raises any serious objections or alternative considerations to Higgs's conclusions – except perhaps in one area.
Having accurate taxonomic assignments would be essential, since it would help greatly in our understanding of the community dynamics, to predict the effect of changes in their composition, and to study key issues in the evolution of the community, such as the extent of horizontal gene transfer (HGT) or the barriers shaping the species.
Even so, fragmentation will remain an issue to watch in the evolution of VR as a mobile technology, and one that could make for incredibly unsatisfying experiences if not handled correctly, at least based on the experience Oculus has had with what qualifies as an enjoyable VR end-user engagement.
Many articles in this issue explore the evolution of complex organs, like eyes.
Evolution of protein coding sequences remains an obscure issue in the molecular evolution of both prokaryotes and eukaryotes.
The remaining issue is the evolution of genes that show specificity in male reproductive tissues.
