"issue hinders" is correct and usable in written English
You could use it when you want to describe something that is blocking progress or causing a problem. For example, "The lack of funding is the main issue that hinders our progress on the project."
The lack of an ideal chronic TMP animal model was initially brought to attention in 2007[12], as this issue hinders the development of new treatment.
The absence of an ideal chronic TMP animal model in the current literature has been brought to attention in recent years[3, 11, 12], as this issue hinders development of treatments for chronic TMP in a clinical setting.
Unfortunately, crystal phase segregation between ZnO and MgO is observed for Mg concentration higher than 36 at.%, owing to the different crystal structure and large lattice mismatch between ZnO and MgO, which issue hinders the developing of ZnMgO-based optoelectronic devices [19].
Inadequate cycle stability is a major issue hindering practical application of lithium sulfur (Li-S) batteries.
Structural failure of polyaniline (PANI) stemmed from repeated swelling-shrinkage during Faradic process represents an imminent issue hindering the real application of this material for advanced energy storage.
Han et al. (2008) suggested that the data imbalance issue hindered the bioactivity classification accuracy.
Besides lack of sequence conservation among lincRNAs, another major issue hindering functional prediction is the lack of validated data.
Our study found that the perceived cost of health services emerged as a major issue hindering community members from utilizing antenatal and postnatal care services.
Many papers discuss how the wider political contexts that efforts to engage men and boys are situated in, particularly those of racism (Dworkin et al. this issue; Ratele this issue; Shefer et al. this issue) and unemployment/economic marginalisation (Dworkin et al. this issue; Flood this issue; Jewkes et al. this issue; Ratele this issue; Stern et al. this issue), hinder gender justice work.
If environmental and other issues hinder performances in Beijing, he said, "you will have damaged a whole generation of athletes".
But a familiar array of issues hindered the Giants (5-2), whaveave struggled to establish a running game and did so again despite the return of the injured guard Chris Snee and the backup running back Brandon Jacobs.
