Sentence examples for issue functional from inspiring English sources

As a major public health issue, functional constipation negatively affects health-related quality of life and is associated with substantial costs.

In part to address this issue, functional imaging is increasingly used to assess clinical response, and especially to provide information on the development of new therapies[ 43 ].

Similar to many registration clinical trials facing limited resource issues, functional impairment was measured by the SDS as one of the secondary endpoints, and our clinical trial did not employ additional informant assessment such as clinician-reported measures of functioning or performance-based assessments to validate the self-reported functioning outcomes.

Beyond technical issues, functional HER2 protein up-regulation on CTCs cannot be excluded, and the acquisition of HER2 amplification during the course of the disease has been suggested [ 74].

The general issue of functional reorganization of language functions has been addressed mainly in studies of patients with brain damage but also in studies of healthy ageing.

The discovery of new genes and annotation of gene function was believed to be an important issue in functional genomics research.

In considering the issue of functional decline, any 'clinically significant change' over time is not only a function the starting and ending levels of functional status.

On the important issue of functional disability, within the proposed criteria there is a description of 'generally mild functional impairment for complex tasks, but basic ADLs [activities of daily living] should be preserved' ([ 2], p. 4).

The multiple PSY genes highlight the issue of functional diversity because of the potential to acquire a novel function, subfunctionalize or even lose the original function [ 67, 68].

The results, which will be reported in a forthcoming issue of Functional Ecology, suggest that echelon swimming is the underwater equivalent to carrying a child.The discovery could also explain why there are not more wild dolphins.

This chapter focuses on the issue of functional adjacency in animal facility.