Delays in issuing changes in the alert level may result in disasters for hikers or people residing in the vicinity of the volcano.
As obesity and high blood pressure are on the rise along with a number of other health issues, changes in the modern diet are very much to blame, and Prescott seeks to answer the question of why and how our tastes often lead us to eat foods that are not the best for our health.
Kinky Boots touches on a number of relevant issues (changes in the economy -- especially in regards to manufacturing -- and the increasing visibility of queer people).
The barriers found were similar to those identified in previous studies: funding issues, changes in the hospital administrative systems, fewer eligible patients than anticipated, problems inherent to some trial types/methodology, (e.g., placebo control), no treatment arms and the difficulties of describing randomisation (McDonald et al, 2006; White et al, 2008a, 2008b).
With respect to the first issue, changes in human paleodiets and fishing practices could be related with the sedimentary filling and rectification of this littoral after the high marine level scenario.
This is an important issue because changes in the concentrations of active metabolites might influence the outcome of therapy; however, results are controversial [ 2, 30, 36, 37].
The issue of changes in the visible choice set is alluded to by Smith (J. Environ. Econom. Manage. 22(1) 71), who identifies this as a primary challenge to Kahneman and Knetsch's (J. Environ. Econom. Manage. 22(1) 57), well-known experimental results.
To address this issue, the changes in the HMGB1 level were examined.
19 We considered only all cause mortality and did not examine the issue of changes in the underlying causes of death.
