Exact(1)
Earlier reports suggest an order of magnitude difference between HM and formula fed infants (10, 11, 13) particularly in our earlier study where one HM fed infants had an absorption of 35% of the isotopic dose.
Similar(59)
Isotopic enrichment in the pre- and post-dose urine samples, the dose given and the local tap water was measured using isotope ratio mass spectrometry (Hydra 20-20; SerCon) at St John's Research Institute, Bangalore, India.
These effects of isotopic substitution are called kinetic isotope effects.
Isotopic enrichment was assessed by isotope ratio mass spectroscopy.
A baseline urine sample was collected on arrival for the measurement of background isotopic enrichment, followed by the administration of an oral dose of O (0·2 g/kg body weight) to each participant at about 09.00 hours.
This complete isotopic mixing (equilibrium) is often used as the basis for dose assessment models.
The enhanced inhibition of DNA synthesis in −/− cells occurred at each dose and time tested, whether assessed by the isotopic or BrdU method.
Isotopic labels were purchased from Cambridge Isotope Laboratories.
The doses were chosen to give sufficient increments and decay curves of the isotopic labels without any major influence on the plasma concentrations of glutamine and phenylalanine, respectively.
Blood for Pb and 206Pb/207Pb ratios was obtained at 14 time points through 30 hr. Results of the isotopic analyses from these subjects indicate that on average 26.2% +/- 8.1 of the administered dose was absorbed.
Isotopic equilibration in body water was determined from a blood sample collected at 1-h post-dose from quick sampling of the saphenous vein.
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