The fourth model included area and isolation, while the fifth included area, isolation and the interaction between area and isolation.
It is widely accepted that temperature, acidity (pH) and ionic strength play an important role in these processes, but studying these aspects in isolation ignores the interaction between variables.
Diseases that lead to an accumulation of bile in the liver tissue almost disqualify these specimens for hepatocyte isolation because the interaction of bile salts with the liver tissue results in highly damaged cells, which are even further damaged during the cell isolation process.
Genetic diversity, adaptation and evolution of a species (Ma et al. 2008) can reflect the species' evolutionary history (e.g. shifts in distribution, habitat fragmentation and population isolation) and the interactions of various processes (such as mutation, genetic drift, mating system, gene flow and natural selection) (Slatkin 1987; Reed and Frankham 2003).
In addition, their thoughts on "difference" and behaviours as "social isolation" might improve by the interaction with a different group of people in similar circumstances.
Since both the frequencies of negative probes and methyl score are associated with variations in mRNA levels, we tested these parameters either in isolation or by assessing the interaction between them (i.e., the frequency of negative probes × methyl score).
While prior studies examine the interactive effect of ATPs with each governance force in isolation, we consider the interactions among ATPs, excess cash, industry competition, and large shareholder ownership altogether.3 Thus, to the best of our knowledge, our study makes the first attempt to provide a comprehensive analysis of such interactive effects in acquisition events.
Although a number of studies proposed various modifications to the original exponential wash-off equation, these studies mostly looked into one parameter in isolation thereby ignoring the interactions between the parameters corresponding to rainfall, catchment and sediment characteristics.
To constrain autophagosome morphogenesis to that of the cargo, TBC1D15 inhibits Rab7 activity and associates with both the mitochondria through binding Fis1 and the isolation membrane through the interactions with LC3/GABARAP family members.
In addition to CsA, isolation of specific inhibitors to the interaction of CAHL and NS5B could allow us to provide effective drug for HCV treatment.
