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New Ebola cases, case isolation events, and contacts undergoing observation were updated with each additional situation report.
First and most simply, at least the early approaches employed in phylogeographic studies for estimating splitting times (i.e., dating isolation events) have been overly simple and without attention paid to variation in evolutionary rates (Peterson 2007).
Phylogeographic patterns of other taxa are also suggestive of colonization and isolation events during proto-Gulf times.
In addition, bottlenecked populations might result from more recent fragmentation and isolation events due to environmental or anthropogenic causes.
These phylogeographic studies use patterns of differentiation and similarity to infer locations and disjunctions of past populations, as well as sequences of historical biogeographic isolation events that led to current patterns [16].
Frequent isolation events could have resulted in allopatric populations and thus promoted speciation [ 79].
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Only one MRSA isolation event per patient per admission-discharge period was included in the analyses.
For analytical simplicity, we considered that times T i s o and T r e c o are scaled in units of N generations, so T i s o = 1 corresponds to an isolation event that occurred N generations ago.
To differentiate a connection from an isolation event, bimodality needs to be associated with a temporal increase of the variance of the modes in the distribution (which depends on the recombination rate; see Figure 1).
These two lineages could be the result of a dispersal process of the ancestral population from the Lower Lerma-Chapala area to the Middle Lerma-Cuitzeo-Zacapu Lerma-Cuitzeo-Zacapu Lerma-Cuitzeo-Zacapu
This bimodality reflects the different possible origins of the two sequences sampled: the two sequences either have a recent common ancestor (i.e., after the reconnection event; first mode in Figure 1A) or an ancient common ancestor (before the isolation event; second mode in Figure 1A).
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