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Improved methods for isolating, engineering, and evolving enzymes give more control over substrate and product specificity and better catalysis inside the cell.
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Although control is sometimes equated with the notion of feedback control (which involves the transmission and return of information)—an isolated engineering invention, not a scientific discipline modern usage favours a wider meaning for the term.
It is argued that oil-spill hazards are more than isolated engineering malfunctions.
The Appld allele was originally isolated by engineering chromosomal aberrations, resulting in deletion of the central region of the Appl gene, while retaining both its 5' and 3' ends [2].
There is so much evidence that schools have been efficient at making isolated courses — electrical engineering, mechanical engineering, and even within electrical engineering you've got hardware, software, analog, digital.
Yeast surface display is an efficient tool for isolating and engineering antibody fragments, both scFv and Fab.
"Mobile devices have made music more of a personal and sometimes isolating experience," Joe Britt, an engineering director at Google, said when he introduced the Q.
As a tool in genetic engineering, isolated microspore cultures have the remarkable quality to produce doubled haploids for plant breeding and gene mapping.
These cells reside within the proliferative stratum of the cambial layer of the perichondrium and periosteum, respectively, and have been isolated for tissue engineering purposes [ 59].
Two evolved strains (RK60-5, RKU90-3) and one evolved strain (KE1-17) were isolated from evolutionary engineering in repetitive batches and chemostat cultivation, respectively.
These data establish SNAP display as an in vitro protein engineering tool for isolating protein binders and provide a framework for troubleshooting affinity selections.
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