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The description of differences in activation patterns of so-called local and global muscles can be made more sensitive by calculating ratios than using isolated relative muscle activity levels [ 20].
One additional benefit to the CWT is that regions of significant power can be isolated relative to an appropriate noise simulation of the input data (for details, see References 10 and 11).
If this is the case, then it should be feasible through the use of internal standards to work out how much endogenous PP1 and R15 are isolated relative to the amounts of PP1 and R15 isolated following over-expression, then to set up an assay to measure comparable amounts of actin.
According to the 16S rRNA phylogeny, the closest isolated relative of M. prima with a genome sequence available is Kosmotoga olearia (fig. 1), a thermophilic bacterium with optimal growth at 65°C, but with an extraordinarily wide temperature range: it can grow well at temperatures as low as 20°C (Dipippo et al. 2009).
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Analysis of meningococcal population structure by MLST suggests that disease-causing meningococci belong to particular groups of related sequence types (STs), termed clonal complexes (CCs), that are overrepresented in disease isolates relative to their carriage prevalences, and that only few so called hyperinvasive lineages are responsible for most disease (reviewed in ref. [7]).
frequencies of virulent (vir) isolates relative to avirulent (Avir) isolates, measured at the end of the growing season.
There are also deletions in the SXT region of the Haitian and Dominican Republic isolates relative to the MJ-1236 reference strain from Bangladesh (Additional file 6: Figure S6).
The higher proportion of synonymous variants in the SSTI isolates relative to the difference in non-synonymous variants did create an overall lower dN/dS ratio in our SSTI isolates (student's t-test, p = 0.04).
Initial investigation into genetic heterogeneity in both rifampicin mono-resistant and MDR isolates relative to M. tuberculosis H37Rv revealed that there were numerous heterogeneous variants present within the genome.
We also compared the variants identified in the H1 and H2 isolates relative to the N16961 reference by PacBio sequencing (H1, H2) with those identified by Illumina sequencing (H1*, H2*).
This fact also explains why we observed, for both NCCLS and Cerner, an inverse relationship between the length of the analysis period and the rate of MRSA, i.e., the greater number of isolates included with shorter periods of analysis meant more MRSA isolates relative to MSSA strains.
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