isolated heart

USAGE SUMMARY

The phrase "isolated heart" is correct and usable in written English.
It can be used to describe a heart that feels alone, disconnected, or emotionally distant, often in a poetic or metaphorical context. Example: "In the midst of a crowded room, she felt like an isolated heart, longing for connection."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

59 human-written examples

Langendorff based isolated heart protocol was employed to analyze the coronary flow resistance.

Biochimie

Grunt, M. et al. Dilatory and inotropic effects of corticotropin-releasing factor (CRF) on the isolated heart.

Nature

We also isolated heart, liver, lung and kidney and investigated in the BLI system at 24 and 72 h post intraperitoneal inoculation.

Nature

THE photodynamic action of diidroquinidine chloridrate on Paramecia, blood serum and isolated heart of a frog has been observed by Pace et al.1.1

Nature

This study was designed to investigate the effects of aspirin on bleeding and transfusion in patients undergoing non-emergent, isolated, heart valve repair or replacement.

Journal of Cardiothoracic and Vascular Anesthesia

The isolated heart determined in Langendorff apparatus and the hemodynamic analysis of rats used to measure the changes of cardiac function extra vivo and in vivo.

Journal of Applied Biomedicine

These microprobes with precisely defined electrode spacing make a useful tool for the spatial and temporal mapping of electrical properties in isolated heart tissues ex vivo.

Biosensors and Bioelectronics

At 48 h following operation, animals were harvested for isolated heart protocol using the Langendorff suspension.

Intensive Care Medicine Experimental

The end-systolic pressure-volume relationship (ESPVR) has been shown to be an afterload-insensitive descriptor of ventricular inotropic state in the isolated heart.

Duke University

The use of lignocaine to prevent or treat reperfusion arrhythmias in the Langendorff model of the isolated heart has been well described [16].

Intensive Care Medicine Experimental

Human-verified similar examples from authoritative sources

Similar Expressions

1 human-written examples

First, the isolated heart or papillary muscle preparations provide interaction of exosomes with different cell types.

Critical Care

Expert writing Tips

Best practice

When describing experimental procedures, use "isolated heart" to clearly indicate that the heart is being studied outside of its natural physiological environment. This is especially important in scientific writing.

Common error

Avoid using "isolated heart" metaphorically to describe feelings of loneliness or detachment. While technically correct, it is overwhelmingly used in a scientific context. If you are trying to describe someone's emotional state, alternatives like "lonely heart" or "detached heart" are more appropriate.

Linguistic Context

The phrase "isolated heart" functions primarily as a noun phrase, where "isolated" acts as an adjective modifying "heart". It describes a heart that has been removed from its natural environment for experimental or study purposes. As Ludwig AI confirms, this is a correct and usable phrase. Examples show its use in scientific literature.

Expression frequency: Very common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

The phrase "isolated heart" is a grammatically sound and highly specific term primarily used within scientific and medical contexts, as validated by Ludwig AI. Its primary function is to denote a heart that has been removed from its natural physiological environment for research or experimental purposes. The register is formal and scientific, with the vast majority of its occurrences found in academic and research papers. While "isolated heart" is technically correct for describing feelings of loneliness, it's more appropriately used in its scientific context. When describing emotional states, alternatives such as "lonely heart" or "detached heart" are better choices. Understanding this nuance is crucial for precise and effective communication, especially in scientific writing.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

ex vivo heart

Focuses on the heart's condition outside a living organism, emphasizing its preparation for experimentation.

perfused heart

Highlights the process of supplying the heart with fluid, which is crucial in ex vivo studies.

Langendorff heart

Specifically refers to a heart prepared using the Langendorff technique, a common method in cardiac research.

explanted heart

Emphasizes the removal of the heart from the body, often for transplantation or study.

harvested heart

Similar to explanted, focusing on the gathering or collection of the heart for research or medical purposes.

heart in vitro

Uses general latin expression to point out heart's experimental environment.

removed heart

Emphasizes the physical act of taking the heart out of the body.

excised heart tissue

Indicates a more detailed focus on the heart's tissue rather than the entire organ.

heart specimen

Refers to the heart as a sample or subject for examination and analysis.

separated heart

Highlights the state of the heart being detached from the rest of the body.

FAQs

How is an "isolated heart" used in scientific research?

An "isolated heart" is used in ex vivo experiments to study cardiac function, pharmacology, and electrophysiology without systemic influences. It allows controlled manipulation of variables to understand specific mechanisms.

What are the limitations of using an "isolated heart" model?

Limitations include the absence of systemic hormonal and neural influences, altered hemodynamics, and potential for tissue damage during preparation. Results may not fully reflect in vivo conditions.

What's the difference between an "isolated heart" and a heart studied in vivo?

An "isolated heart" is studied outside the body, allowing direct control over the environment but lacking systemic interactions. In vivo studies examine the heart within a living organism, preserving physiological context but limiting experimental control.

Are there alternatives to using a completely "isolated heart" in research?

Yes, alternatives include in situ preparations where the heart remains within the chest cavity but is surgically isolated from systemic circulation, and computational models that simulate cardiac function.