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Several polyamine derivatives that have been isolated display high levels of CA isoform selectivity with potencies ranging from millimolar to low nanomolar levels [ 118].
On the contrary, residue 151 of serotype A isolates displays significant evidence (p = 0.29) for positive selection.
We also showed that IBV YN isolate displays more severe pathogenicity than previously characterized strains in China.
All PHBV isolates display classical avihepadnavirus genome architecture.
Ethyl acetate extract and the isolate displayed remarkable sickling inhibitory effects.
Cloned HIVSGD BKPyV isolates displayed active promoters and efficient replication capability in human salivary gland cells.
The 62 isolates displayed wide diversity, since 41 MLVA types (i.e. MTs) were observed, with 26 MTs clustered in 10 MLVA clonal complexes (MCs).
PHBV isolates display a degree of diversity (>78% genome wide pairwise identity) that is comparable to that found amongst all other avihepadnaviruses (>79% genome wide pairwise identity).
A distinct group of CC45 isolates display agr IV alleles.
Breakthrough isolates displayed high levels of phenotypic resistance to ETV in vitro.
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