Sentence examples for isolated deficiencies from inspiring English sources

Secondary to megalin and cubilin loss, isolated deficiencies of certain small-molecular-weight proteins and their ligands (i.e., vitamins) would be predicted.

Isolated deficiencies of one or two pituitary hormones also may occur, often on a heritable basis.

Isolated deficiencies of aldosterone biosynthesis are caused by inactivating mutations in the CYP11B2 gene [ 2, 3].

Isolated deficiencies of human complex I (CI) often cause severe early-onset progressive disease, but the spectrum of disorders associated with this biochemical abnormality is expanding.

ACTH deficiency can occur as part of a multiple pituitary hormone deficiency syndrome (panhypopituitarism) or as an isolated deficiency.

Given the role of MTO1 as an optimizer of mtDNA translation, MTO1 mutations can be associated with any combination of MRC deficiency, from isolated CIV deficiency (Family 2 in this article) to combined CI + CIV deficiency, the most common biochemical signature observed in MTO1 mutant cases, to combined CIV + CIII deficiency, as previously reported [Ghezzi et al., 2012].

Immunoreactivity against this protein was previously reported in a small number of patients with lymphocytic hypophysitis, isolated ACTH deficiency, idiopathic TSH deficiency and other autoimmune diseases.

To corroborate this observation, both ICU and mortality rates were not significantly different in group-2 (mainly including isolated ADAMTS13 deficiencies) and group-3 patients.

However, these general principles are not invariably true, because patients with mtDNA depletion may have isolated complex deficiencies early in the disease course.

Numbers of births with complete information for maternal daily nitrate intake from water sources and other covariables were 227, 94, 415, 1,046, and 1,105, respectively, for all NTDs, isolated limb deficiencies, oral cleft defects, congenital heart defects, and controls.

No abnormality was found in any of the genes known to be involved in either isolated GH deficiency or combined pituitary hormone deficiencies.