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This research entails the use of 112 anticancer compounds from NCI database to develop QSAR and QSTR models that could be used to predict the activity and toxicity of newly designed compounds which are within the applicability domain of the model.
(The example of two models with different predictions, above, illustrated the issue of whether the target chemical was within the applicability domain of the model, explained below).
The objects with the Euclidean distance to the central neuron which is smaller or equal to the limiting Euclidean distance are within the applicability domain.
Stated another way: Is the sample within or outside the model's domain of applicability or what is the degree to which a test compound is within the model's domain of applicability.
The whole data points present in the dataset are within the domain of applicability of the employed models.
The criterion used by this approach to associate a given test sample to be within the domain of applicability can be summarised below.
Thirdly, the study only included subjects whose ages were within the range of 40 70 years, which might limit the external applicability of the study results.
But the real point is not the applicability of a "Saginaw plan" to New York.
In particular we were interested in the applicability of the ICPS within the homecare context.
What makes this new step important is the applicability to already-built power plants.
Another issue is the applicability of expertise-based RCTs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com