It is not an ideal method: since it relies on the length of linkage disequilibrium on one haplotype in relation to the frequency of that haplotype, it may be vulnerable to different sampling strategies that could alter the apparent frequency of that haplotype.10 Allele-specific recombination rates could also produce a similar effect.
But these areas are lagging behind in socioeconomic development and are vulnerable to different disasters, environmental degradation, and global climate change.
Komen alone has invested $17 million into early detection research, including 20 new grants this year to explore imaging technology, genetic testing, biomarkers and tests to help predict which women are vulnerable to different forms of breast cancer.
In the analysis of population vulnerability to climate change, it is important to recognize that specific populations will be vulnerable to different climate-sensitive outcomes.
It has been argued that self-reported PA is vulnerable to culturally different interpretations, and hence, that the validity and reliability of objective measures of PA is superior to subjective measures [14].
In contrast, when HSPG-bound VEGF is vulnerable to degradation, the different grading of VEGF isoforms seen in vivo (e.g. Figure 1A) is recapitulated [ 7, 21, 22, 39].
Secondly, our primary endpoint of clinical patency at six weeks is vulnerable to observer bias with different clinicians interpreting patency differently.
Although this means of assessment has proven useful, it is vulnerable to reporting biases from different sources (e.g., personality, culture, memory, and assessment conditions) [ 25- 27].
