Paclitaxel, which mediates its cytotoxic action via NF- κB pathway, is vulnerable to develop resistance in the presence of hypoxic tumour microenvironment, with activation of NF- κB transcription factor, which induces serine phosphorylation and also regulates BCL-2, an antiapoptotic protein, preventing cell death and promoting tumorigenesis [ 76].
Those with a weakened immune system or who are already hospitalised are vulnerable to developing the condition.
An implication of the present study is that significant numbers of people who were present on 9/11 could be vulnerable to developing chronic diseases many years later.
Children taking these medications can quickly become obese and are vulnerable to developing diabetes, hypertension and other disorders related to obesity.
And the question of physical activity ignores the lack of nutritional value offered by these drinks as well as their negative impact on oral health and those who may be vulnerable to developing type 2 diabetes.
Unaccompanied refugee minors (URMs) are a group who are vulnerable to developing posttraumatic stress symptoms (PTSS).
Nevertheless, since these patients require immunosuppressive therapy, they are vulnerable to developing postoperative infections.
Children, young people and adults with IDD are vulnerable to developing mental ill health and face health inequalities [ 3, 4].
42 44 Furthermore, previous research has stated that women are vulnerable to developing and sustaining musculoskeletal pain conditions.
Physicians may be vulnerable to developing depressive symptoms because of their everyday exposure to patient suffering, disease, death, emergency and unreasonable patient demands [ 34, 43, 44].
