While in the top row, the misalignment between PET and MR is very easily detectable, it would be harder to identify when using a realistic PET image.
First, there is very little detectable accumulation of mutations over time, as most mutations are already observed at week 8. Second, the common mutations (that is, those found in many sequences across all time points; Figure 4) are not enriched for R mutations when compared with the rare mutations (that is, those found in only a few sequences and in one time point).
Moreover, the radial position of the data points obtained for the MWL-AUC is very reproducible without detectable radial variation, from repeated measurements.
It should be noted that in different types of cells, the cytoplasmic nucleolin signal observed by confocal immunofluorescence microscopy is very weak and is detectable only after scanning at an elevated intensity.
In the case of Physcomitrella, the PSII core band is very faint and hardly detectable, while the PSII-LHCII supercomplexes are more abundant, especially with respect to Arabidopsis, suggesting a much stronger association between core and antenna polypeptides for PSII in this moss.
It seems the phenotype of ppccd8 is very subtle and only detectable in plants with fewer than 20 leaves.
As we are using a single mid-latitude observatory in contrast to a wide spread of observatories, it is very likely that some SSCs detectable in higher latitudes fall below our detection threshold, leading to a lower percentage of detection.
Although no Sp2 protein, neither full-length nor a C-terminal truncated fragment was detectable, it is very likely that the glutamine-rich N-terminal part of Sp2 is expressed at a very low level.
However, natural or artificially released hard gamma emitters can be easily found as minimum detectable activity is very low.
While this rate of internal pair production is very small, there is a detectable peak of 511 keV photons which exceeds the continuous spectrum of bremsstrahlung photons and these 511 keV photons can be detected and imaged using conventional PET imaging [ 66].
