When adherence to the prescribed drug dosage is known, true dose response can be validly estimated, while non-compliance with the nominal prescribed dosage causes unintended variability in actual drug exposure and ensuing difficulty in determining dose response.
For the present analyses, we have assumed that airborne endotoxin is the "true" exposure and that average airborne exposure in the first months of life can be validly estimated by a single measurement collected for an average of 1.5 days.
When the interest is in etiologic studies using CAC as outcome parameter, our findings show that risk factor relations will be validly estimated since none of the risk factors relates to measurement error.
"If a person is validly registered to vote, the signature should count".
For many applications, the growth of an object is validly described by assuming least cost or gravitational rules.
Nonetheless, Lewis recognized the need to assure ourselves rationally that the frequency as validly estimated from the data is closely in accord with the actual frequency and that there is nothing in the case at hand affecting the occurrence of the property which isn't taken into account in the specification of the reference class.
In locations where large numbers of tuberculosis patients are diagnosed and treated by private sector practitioners who are not typically included in drug resistance surveys, targeted surveys for assessing drug resistance are required to validly estimate resistance.
Therefore, assuming that the time series data are more or less complete and smooth or can be validly smoothed (see later) —one can estimate the slope of the time course at each time point and substitute the slopes for the derivatives.
There were insufficient data to validly estimate the odds ratio for TB disease.
It is important, once a model has been fitted, to estimate whether any predictions stemming from it can be validly extended to other samples or to the same participants in the future.
Most MPs wouldn't be validly elected if that was the test.
